The oncopathogen Helicobacter pylori benefits from the gastric mucus layer pH gradient for timely escape from shedding cells and mucus. By chemotaxis-driven return to the epithelium, H. pylori successfully establishes life-long infection through daily selection of the best-adapted and most prosperous bacteria.
Check out the paper at: http://www.cell.com/cell-host-microbe/fulltext/S1931-3128(17)30075-6
Bugaytsova J.A., Björnham O., Chernov Y.A., Gideonsson P., Henriksson S., Mendez M., Sjöström R., Mahdavi J., Shevtsova A., Ilver D., et al. (2017) Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence. Cell Host Microbe. 21.
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